2,4-Difluorophenylzinc bromide
2,4-Difluorophenylzinc bromide
CAS: 517920-79-5
Molecular Formula: C6H3BrF2Zn
2,4-Difluorophenylzinc bromide - Names and Identifiers
| Name | 2,4-Difluorophenylzinc bromide |
| Synonyms | 2,4-Difluorophenylzinc bromide 2,4-DIFLUOROPHENYLZINC BROMIDE |
| CAS | 517920-79-5 |
2,4-Difluorophenylzinc bromide - Physico-chemical Properties
| Molecular Formula | C6H3BrF2Zn |
| Molar Mass | 258.38 |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
2,4-Difluorophenylzinc bromide - Risk and Safety
| Hazard Symbols | F - Flammable |
2,4-Difluorophenylzinc bromide - Introduction
2,4-Difluorophenylzine bromide is an organic compound with the chemical formula C6H3BrF2Zn. It is a white solid, stable at room temperature. Its main use is as an important substitution reagent in organic synthesis.
The preparation method of 2,4-Difluorophenylzinc bromide is usually obtained by reacting zinc bromide and 2,4-difluorobromobenzene. Attention should be paid to operating conditions and safety measures during preparation.
This compound is generally used as a Grignard reagent (Grignard reagent) in organic synthesis, and can react with various carbonyl compounds. It can participate in allylation, borane, aromatic nucleus substitution and other reactions, thereby constructing carbon-carbon bonds and carbon-heteroatom bonds. Therefore, it has important application value in organic synthesis.
When using 2,4-Difluorophenylzinc bromide, you need to pay attention to its irritation to the skin and eyes. Wear appropriate protective gloves, goggles and laboratory clothing when using. In addition, care should be taken to avoid contact with oxygen and water to avoid dangerous reactions. If ingested or inhaled, seek medical attention immediately.
The preparation method of 2,4-Difluorophenylzinc bromide is usually obtained by reacting zinc bromide and 2,4-difluorobromobenzene. Attention should be paid to operating conditions and safety measures during preparation.
This compound is generally used as a Grignard reagent (Grignard reagent) in organic synthesis, and can react with various carbonyl compounds. It can participate in allylation, borane, aromatic nucleus substitution and other reactions, thereby constructing carbon-carbon bonds and carbon-heteroatom bonds. Therefore, it has important application value in organic synthesis.
When using 2,4-Difluorophenylzinc bromide, you need to pay attention to its irritation to the skin and eyes. Wear appropriate protective gloves, goggles and laboratory clothing when using. In addition, care should be taken to avoid contact with oxygen and water to avoid dangerous reactions. If ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-10 22:29:15
